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Hemodynamic Fluid-Structure Interaction of Cardiovascular System

During the past two decades, FSI simulation has become the most promising solution method to solve the hemodynamic problem existing in the clinical cardiovascular system. However, the complexity of cardiovascular and artificial heart models causes the deficiency of the existing FSI simulation package towards the clinical demands. First of all, the space embraced by the cardiovascular system is irregular and asymmetric, and the vascular wall is laminated as well. In order to obtain a reliable numerical result to describe the real situation, the number of mesh cell needs to be enormously raised inside the vascular wall, leading to a large-scale and very time-consuming computation. Secondly, the mechanical property of the vascular wall is considered as a complex anisotropic hyperelastic material. The complicated constitutive relation of such material may significantly increase the computational cost and raise the convergence requirement for FSI simulation. Thirdly, because a large deformation may take place in the vascular wall during a cardiac cycle, the traditional FSI algorithm cannot tackle a largely deformed vascular in an efficient and accurate fashion, and always results in a nonconvergent or even a failed numerical computation. Fourthly, the co-existence of deformation and rotation on the elastic artificial heart pump challenges the existing structure model as well as the implementation of arbitrary Lagrangian-Eulerian (ALE) approach - a popularly employed method in FSI algorithm. The complicated motion of artificial heart makes the traditional ALE method fail to generate a shape-regular moving fluid mesh which shall conform with the structure mesh all the time. Finally, a high speed revolution occurring on the artificial heart pump introduces another large difficulty to the traditional FSI simulation, where, because the rotational spaces interact with the surrounding stationary spaces, it is an art of numerical method how to remain the rotating mesh always conforming with the stationary mesh through the interfaces.

In this project the PI devoted his research to the new modeling and numerical techniques for the bloodstream-vascular-stent graft/artificial heart pump interaction problems, aiming at overcoming the aforementioned numerical difficulties and challenges, and developed advanced numerical methodologies to improve the efficiency and accuracy of corresponding FSI simulations, as demonstrated below by some well-done numerical simulations.

 

  • A growing aneurysm

 

  • An expanding stent graft inside the blood vessel

 

  • Blood flow-aneurysm interactions

 

  • Blood flow-aneurysm-stent graft interactions

 

  • Rotating artificial heart pump-blood flow interactions

 

 

Last updated: 01/17/2021

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